The college football odds will continue to be updated throughout the week. On Saturday, it will be #24 Kansas vs #3 Texas, #13 LSU vs #20 Ole Miss and #11 Notre Dame vs #17 Duke. There are four games between ranked teams, starting with #10 Utah vs #19 Oregon State on Friday night. NC State (3-1) got past Virginia 24-21 on Friday night. Louisville (4-0) opens as a 2.5-point favorite after staying unbeaten Saturday with a 56-28 victory over Boston College. Louisville visits North Carolina State on Friday to being the Power Five portion of the Week 5 college football schedule. A look at the college football Week 5 opening odds can be found below with early picks.One of the week’s top matchups features #17 Duke hosting #11 Notre Dame.The Power Five portion of college football Week 5 begins Friday night with Louisville visiting North Carolina State.Mandatory Credit: David Butler II-USA TODAY Sports
East Hartford, Connecticut, USA Duke Blue Devils quarterback Riley Leonard (13) is congratulated after scoring a touchdown against the UConn Huskies in the second quarter at Rentschler Field at Pratt & Whitney Stadium.
